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PNEUMOCYSTIS JIROVECII COLONIZATION IN CHRONIC PULMONARY DISEASE

Autores

Gutierrez, S. , Respaldiza, N. , Campano, E. , Martinez-Risquez, M. T. , Calderon, E. J. , DE LA HORRA PADILLA, CARMEN

Publicación externa

Si

Medio

Parasite

Alcance

Article

Naturaleza

Científica

Cuartil JCR

Cuartil SJR

Impacto SJR

0.727

Fecha de publicacion

01/05/2011

ISI

000291240500002

Abstract

Pneumocystis jirovecii causes pneumonia in immunosuppressed individuals. However, it has been reported the detection of low levels of Pneumocystis DNA in patients without signs and symptoms of pneumonia, which likely represents colonization. Several studies performed in animals models and in humans have demonstrated that Pneumocystis induces a local and a systemic response in the host. Since P jirovecii colonization has been found in patients with chronic pulmonary diseases it has been suggested that P jirovecii may play a role in the physiopathology and progression of those diseases. In this report we revise P jirovecii colonization in different chronic pulmonary diseases such us, chronic obstructive pulmonary disease, interstitial lung diseases, cystic fibrosis and lung cancer.

Palabras clave

Pneumocystis jirovecii; colonization; chronic pulmonary disease