Title Metagenomic analysis of bronchoalveolar lavage samples from patients with idiopathic interstitial pneumonia and its antagonic relation with Pneumocystis jirovecii colonization
Authors Friaza, Vicente , DE LA HORRA PADILLA, CARMEN, Rodriguez-Dominguez, Mario J. , Martin-Juan, Jose , Canton, Rafael , Calderon, Enrique J. , del Campo, Rosa
External publication Si
Means JOURNAL OF MICROBIOLOGICAL METHODS
Scope Article
Nature Científica
JCR Quartile 3
SJR Quartile 2
JCR Impact 2.018
SJR Impact 0.954
Publication date 01/07/2010
ISI 000279567700016
DOI 10.1016/j.mimet.2010.03.026
Abstract Idiopathic interstitial pneumonias are interstitial lung diseases of unknown etiology which prognosis is usually fatal. Microbiota associated to bronchoalveolar lavage from 20 patients with negative bacterial cultures was explored by 16S-rDNA PCR-DGGE, showing a clearly negative relation among the presence of P. jirovecii and bacterial colonization. This is the first report of in vivo antagonistic relation among fungi and bacteria. (C) 2010 Elsevier B.V. All rights reserved.
Keywords PCR-DGGE; Idiopathic interstitial pneumonia; Pneumocystis jirovecii; Metagenomic
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